Our research group tackles the following questions:

  1. Why does stress may increase or decrease food intake?
  2. Why do sweets may comfort us in stressful situation?
  3. Why do chronic stress and repeated food restriction may trigger binge eating?
  4. Why is feeding coming out of the control and food consumed in quantity which is much higher than needed during binge eating episodes?
  5. Why do males and females differently respond to stress?
  6. Why is the prevalence of eating disorders much higher for women than for men?

About us

About us

Our research is focused on the neuronal mechanisms of feeding behavior. Understanding the role of particular molecules, neurons and neuronal networks in food intake regulation requires development of adequate animal models. In our laboratory we have developed a rat model of binge eating. In addition, we study the neuronal and molecular mechanisms of feeding behavior in rats with genetic and diet obesity. Furthermore, our rat models include males and females to study sex-specific regulation of food intake.

We use the following methods:

  1. Molecular biology: PCR, gene cloning, gene transfection, in situ hybridization.
  2. Detection of plasma hormones: radioimmunoassay, ELISA.
  3. Behavioral experiments: studying of feeding behavior using Med Associates automatic behavioral chamber.
  4. Neuroanatomy: immunohistochemistry, retrograde and anterograde neuronal tracing, 3D neuronal reconstruction.
  5. Electophysiology: multichannel recording of neuronal activity in freely behaving rats.